秀丽隐杆线虫研究为太空旅行提供启示

The astrophysicist（天体物理学家） Stephen Hawking believes that if humanity is to survive we will have to up sticks and colonise space. But is the human body up to the challenge? Scientists at The University of Nottingham believe that Caenorhabditis elegans (C. elegans), a microscopic worm which has biologically similarities to human beings, could help us understand how humans might cope with long-duration space exploration.

Their research, published Nov. 30, 2011 in Interface, a journal of The Royal Society, has shown that in space the C. elegans develops from egg to adulthood and produces progeny just as it does on earth. This makes it an ideal and cost-effective experimental system to investigate the effects of long duration and distance space exploration.

In December 2006 a team of scientists led by Dr Nathaniel Szewczyk from the Division of Clinical Physiology in the School of Graduate Entry Medicine blasted 4,000 C. elegans into space onboard the Space Shuttle Discovery. The researchers were able to successfully monitor the effect of low Earth orbit (LEO) on 12 generations of C. elegans during the first three months of their six month voyage onboard the International Space Station. These are the first observations of C. elegans behaviour in LEO.

Dr Szewczyk said: "A fair number of scientists agree that we could colonise other planets. While this sounds like science fiction it is a fact that if mankind wants to avoid the natural order of extinction then we need to find ways to live on other planets. Thankfully most of the world's space agencies are committed to this common goal.

"While it may seem surprising, many of the biological changes that happen during spaceflight affect astronauts and worms and in the same way. We have been able to show that worms can grow and reproduce in space for long enough to reach another planet and that we can remotely monitor their health. As a result C. elegans is a cost effective option for discovering and studying the biological effects of deep space missions. Ultimately, we are now in a position to be able to remotely grow and study an animal on another planet."

Many experts believe the ultimate survival of humanity is dependent upon colonisation of other planetary bodies. But we face key challenges associated with long term space exploration. Radiation exposure and musculoskeletal（肌骨骼的） deterioration（恶化，退化） are thought to be two of the key obstacles to successful habitation beyond LEO.